Look very closely at this picture of the Sun. See the speck at the left near the equator, and teh even tinier speck next to that?
That is the International Space Station and the Space Shuttle undocking from it, taken on September 17, 2006.
(Via Bad Astronomy, which counts this No. 5 on its list of the top ten astronomy shots of 2006).
Below is a closeup showing the station and shuttle in more detail.